乳酸菌発酵物質 Novel Kefir PFT 研究発表

Mamdooh Ghoneum Ph.D. List of publications and conferences

I- List of Published Research Articles – Peer Revied

1- Ghoneum M, Gimzewski J. Apoptotic effect of a novel kefir product, PFT, on multidrug-resistant myeloid leukemia cells via a hole-piercing mechanism. Int J Oncol. 44(3):830-7 (2014).

2- Ghoneum M and Felo N. Selective induction of apoptosis in human gastric cancer cells by lactobacillus kefiri (PFT), a novel kefir product.  Oncol Reports. 34(4):1659-66 (2015).

3- Ghoneum M, Felo N, Agrawal S and Agrawal A. A novel kefir product (PFT) activates dendritic cells to induce CD4+T and CD8+T cell responses in vitro. Int J Immunopathol  Pharmacol. 28(4): 488-96 (2015).

4- Badr El-Din NK, Shabana S, Abdulmajeed BA and Ghoneum M. A novel kefir product (PFT) inhibits Ehrlich ascites carcinoma in mice via induction of apoptosis and immunomodulation. BMC Complementary Medicine and Therapies 20(1):127 (2020).

5- Ghoneum M, Abdulmalek S and Deyu P. Reversal of age-associated oxidative stress in mice by PFT, a novel kefir product. Intl J Immunopath Pharmacol.34:2058738420950149 (2020).
6- El Sayed NS, Kandil EA, Ghoneum MH. Enhancement of insulin/PI3K/Akt signaling pathway and modulation of gut microbiome by probiotics fermentation technology, a kefir grain product, in sporadic Alzheimer’s disease model in mice. Front Pharmacol. 12:666502 (2021).

7- El Sayed NS, Kandil EA, Ghoneum MH. Probiotics fermentation technology, a novel kefir product, ameliorates cognitive impairment in streptozotocin-induced sporadic Alzheimer’s disease in mice. Oxid Med Cell Longev.2021:5525306 (2021).

 

II-  List of National and International Symposia

8- Ghoneum M and Ghoneum, A. The Apoptotic effect of Lactobacillus kefiri P-IF on human myeloid leukemia HL60/AR cancer cells. American Association for Cancer Research (AACR), special Conference on Tumor Immunology: Multidisciplinary Science Driving Basic and Clinical Advances in Miami, Florida USA.  December 2-5,(2012).

9- Ghoneum M, Henary M, and Seto Y. Apoptotic effect of thymus extract plus Lactobacillus kefiri P-IF (Thymokefiri) on human myeloid leukemia (HL60/AR) cancer cells. American Association for Cancer Research (AACR) in Washington DC, USA. April 6-10, (2014).

10-Ghoneum M.  Sensitivity of metastatic breast cancer (4T1) cells to apoptotic effect by Lactobacillus kefiri P-IF via a mechanism that involves hole piercing in cancer cells. Annual meeting American Association for Cancer Research (AACR) in San Diego, California USA. April 5-9,(2014).

11-Badr El-Din NK, Shabana S, Abdulmajeed BA and Ghoneum M. Chemopreventive potential of Lactobacillus kefiri P-IF, a novel kefir product, on Ehrlich ascites carcinoma cells. Annual meeting American Association for Cancer Research (AACR) in in Washington, D.C. USA. April 1-5,(2017).